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Abvance Therapeutics

Nashville, Tennessee, United Statesabvancetherapeutics.com ↗

Ownership: Private
Development stage: Preclinical

Overview

Abvance Therapeutics has developed ABV100/ABV101, a novel coformulation of short acting insulin and glucagon designed to improve glycemic control while reducing the risk of hypoglycemia in people with diabetes who require rapid acting insulin. Proof-of-concept studies in type 1 diabetes patients have validated the glucose-dependent interaction between these peptides. The company recently secured $3.9 million from the Helmsley Charitable Trust to advance preclinical development[3][4]. Early clinical data suggest potential for better glycemic control with fewer hypoglycemic events compared to standard therapies[5].

Therapeutic areas: Endocrinology
Modalities: Peptides (insulin and glucagon combination)Protein-based therapeutics
Industry: Biotech

Drug pipeline

3 assets

ABV100

2 more assets in the full pipeline.

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Partnerships

Vanderbilt University Cherrington Lab (foundational research)Helmsley Charitable Trust funding partner[3][4]

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