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Accent Therapeutics

Lexington, Massachusetts, United Statesaccenttx.com ↗

Ownership: Private
Employees: ~50
Development stage: Phase 1

Overview

Accent Therapeutics has two clinical-stage programs: ATX-559 (DHX9 inhibitor) and ATX-295 (KIF18A inhibitor). The first patient was dosed in the Phase 1/2 trial for ATX-295 in April 2025, and both lead assets have received FDA Fast Track designation. ATX-559 is being evaluated in patients with BRCA1/2-deficient breast cancer and MSI-H/dMMR solid tumors, while ATX-295 is being tested in patients with advanced solid tumors including ovarian cancer.

Therapeutic areas: Oncology
Modalities: Small molecules
Industry: Biotech

Drug pipeline

6 assets

ATX-559

5 more assets in the full pipeline.

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