Company intelligence / Profile preview

Acelot

Santa Barbara, California, United Statesacelot.com ↗
Ownership
Private
Employees
~50
Development stage
Other
01

Overview

Acelot’s lead program ACE-2223 is a first-in-class orally bioavailable small molecule that disrupts misfolded TDP43 and restores its function. Preclinical data show blood-brain barrier permeability and efficacy in reducing pathological TDP43 aggregates as well as improving neuroinflammation and motor function. The company has a robust pipeline of hit-to-lead discovery compounds across multiple indications.

Therapeutic areas
OncologyEndocrinologyNeurology
Modalities
Small molecules
Industry
Biotech
02

Drug pipeline

2 assets

ACE-2223-1

1

1 more asset in the full pipeline.

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