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Achilles Therapeutics is a clinical-stage biopharmaceutical company developing personalized T cell therapies for solid tumors. The company utilizes its proprietary PELEUS bioinformatics platform to identify clonal neoantigens—unique mutations present in all of a patient's tumor cells but not in healthy tissue. Their lead product candidates, derived from the patient's own T cells, are designed to target these clonal neoantigens to achieve a more potent and durable anti-tumor response. Achilles is currently evaluating its therapies in clinical trials for non-small cell lung cancer and melanoma.
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