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Acuity Pharmaceuticals

Philadelphia, Pennsylvania, United Statespharmaacuity.com ↗
Ownership
Private
Development stage
Phase 2
01

Overview

Acuity Pharmaceuticals developed Cand5, the first clinical use of gene-silencing technology via RNA interference targeting VEGF for wet age-related macular degeneration and diabetic eye diseases. The company also licensed N-chlorotaurine (NCT), a small molecule anti-infective with broad-spectrum activity for ophthalmic infections. Both programs showed promising safety and efficacy signals in early-phase trials before the company's acquisition by OPKO Health in June 2011.

Therapeutic areas
OphthalmologyInfectious Diseases
Modalities
Small moleculeRNA therapy (specifically RNA interference)
Industry
Biotech
02

Drug pipeline

2 assets

NPI-001

Phase 1/2
Indications
Retinitis pigmentosa, Usher syndrome

1 more asset in the full pipeline.

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03

Partnerships

Pathogenics, Inc. – licensor of N-chlorotaurine ophthalmic rights

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