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Adaptin Bio

Charlotte, North Carolina, United Statesadaptinbio.com ↗

Ownership: Private
Development stage: Other

Overview

Adaptin Bio has developed a proprietary BRiTE technology that enables targeted delivery of therapeutics across the blood-brain barrier. Their lead candidate, APTN‑101 targeting EGFRvIII in glioblastoma, has shown strong preclinical efficacy and safety. In September 2024, the FDA cleared their IND application for APTN‑101 to begin a first-in-human Phase 1 trial in GBM patients. Preclinical data demonstrated high specificity against tumor antigen-expressing glioma cells and significant brain distribution with non-toxicity.

Therapeutic areas: OncologyNeurology
Modalities: Bispecific T cell engagers (BRiTE platform)Engineered polyclonal T cells
Industry: Biotech

Drug pipeline

1 asset

APTN-101

Unknown

Partnerships

Lucius Partners provides strategic support and investment.Laidlaw & Company mentioned as an investor/supporter.No major pharma partnerships publicly announced yet.

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