zotiraciclib
Phase 1- Indications
- High-grade gliomas
Company intelligence / Profile preview
Adastra Pharmaceuticals was a clinical-stage biopharmaceutical company focused on developing small molecule therapies for aggressive cancers. Its lead program zotiraciclib targeted multiple cyclin-dependent kinases and reached Phase I/II in high-grade gliomas before being acquired by Cothera Bioscience in October 2021. Another candidate, apricoxib targeting COX‑2 for HER2-positive breast cancer, was discontinued. The company appears to have ceased independent R&D following the asset transfer[1][5][6].
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