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Adolore BioTherapeutics

Delray Beach, Florida, United Statesadolore.com ↗

Ownership: Private
Development stage: Phase 2

Overview

Adolore has demonstrated preclinical proof-of-concept for its CA8*-based gene therapies, showing long-lasting, locally acting analgesia in models of chronic osteoarthritis knee pain and erythromelalgia. The company is progressing toward IND filings and first-in-human clinical studies with support from NIH/NINDS grants. Manufacturing scale-up and additional preclinical animal studies are ongoing, with clinical batch production targeted for 2025 and human trials expected to begin in the first half of 2026

Therapeutic areas: CardiovascularRheumatology
Modalities: Gene therapyProtein therapeutics
Industry: Biotech

Drug pipeline

8 assets

ADB-103

Preclinical

7 more assets in the full pipeline.

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Partnerships

Advance Biological Laboratories / Institute Merieux subsidiary – manufacturing process development under NIH/NINDS HEAL program contract

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