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Adrastea Pharma is a French biotechnology company focused on developing disease-modifying therapies for neurodegenerative disorders, specifically targeting Parkinson's disease associated with GBA1 mutations. The company's approach centers on restoring the activity of the lysosomal enzyme glucocerebrosidase (GBA) using small molecule activators. By addressing the lysosomal dysfunction that leads to alpha-synuclein accumulation, Adrastea aims to slow or halt disease progression in patients with GBA-related Parkinson's. The firm is part of a new wave of precision medicine companies targeting genetically defined subpopulations in neurology.
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