Advanced Polymer Systems

Advanced Polymer Systems, now operating as Heron Therapeutics, is a commercial-stage biotechnology company that pioneered advanced drug delivery technologies to improve the therapeutic profile of existing medicines. The company is best known for developing the Microsponge and Biochronomer polymer platforms, which allow for the sustained and controlled release of active ingredients. Its technology has been successfully applied to a wide range of products, from topical dermatological treatments like Retin-A Micro to sophisticated injectables for oncology supportive care and pain management. Following its rebranding to AP Pharma and later Heron Therapeutics, the company has transitioned into a commercial-stage entity with a focus on acute care and oncology. Its current portfolio includes FDA-approved products such as SUSTOL and ZYNRELEF.