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Aeovian's lead candidate AV078, a first-in-class CNS-penetrant selective mTORC1 inhibitor, has completed Phase 1 dosing in healthy volunteers and advanced to Phase 2 studies in adult and pediatric patients with TSC refractory epilepsy[2][3]. The company is conducting preclinical work in age-related and chronic conditions characterized by inflammation and metabolic dysfunction[6].
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