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Aerovate Therapeutics

Waltham, Massachusetts, United Statesaerovatetx.com ↗

Ownership: Public · AVTE
Employees: ~30
Development stage: Other

Overview

The Phase 2b IMPAHCT trial for AV-101 failed to meet its primary endpoint for improvement in PAH compared to placebo for any of the studied doses. The drug also failed to show meaningful improvements in the secondary endpoint of change in six-minute walk distance. As a result, the Phase 3 and long-term extension arms were stopped, and the company announced a 78% workforce reduction in July 2024[10].

Therapeutic areas: Rare DiseasesCardiovascular
Modalities: Small molecules (specifically inhaled dry powder formulation)
Industry: Biotech

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