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Aerpio Therapeutics

Cincinnati, Ohio, United Statesecosystem.plai.mx ↗

Ownership: Private
Employees: ~50
Development stage: Phase 2

Overview

AKB‐9778, a first-in-class Tie2 activator, completed a Phase IIb trial in nonproliferative diabetic retinopathy. Results showed reduction in intraocular pressure and improved kidney function over 48 weeks. In combination with Lucentis for DME, it achieved greater retinal drying than ranibizumab alone. Some positive secondary endpoints were observed.[10][5]

Therapeutic areas: Ophthalmology
Modalities: Small moleculesMonoclonal antibodies[2][3]
Industry: Biotech

Drug pipeline

1 asset

AKB-9778

Phase 2

Indications: Diabetic retinopathy

Partnerships

Novartis BioVentures and other VCs as investors; no major pharma co-development partnerships disclosed pre-merger.[8]

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