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Affectis Pharmaceuticals AG

Dortmund, Nordrhein-Westfalen, Germany

Ownership: Private
Employees: ~50
Development stage: Preclinical

Overview

Affectis Pharmaceuticals AG is a German biopharmaceutical company focused on developing novel small molecule drugs targeting neurodegenerative, neuroinflammatory, and psychiatric disorders. Its lead assets target the P2X7 receptor and COX‑2, with at least one program having reached Phase 2 clinical trials in depression. The company has also developed brain‑penetrant oral compounds and has ongoing collaborations to advance its pipeline.[1][9][10]

Therapeutic areas: EndocrinologyPsychiatryNeurology
Modalities: Small molecules[1][2][5]
Industry: Biotech

Drug pipeline

1 asset

AFC-5128

Pre-clinical

Indications: Neurodegenerative diseases

Partnerships

Merck Serono(agreement to develop oral drugs for neurodegenerative diseases targeting theP₂ X₇receptor )[1 ]Dalton Pharma Services(contract services agreement )[1 ]Lead Discovery Center GmbH(close collaboration since2014 )[5 ]

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