Company intelligence / Profile preview

Afimmune

Dublin, Leinster, Irelandafimmune.com ↗
Ownership
Private
Employees
~10
Development stage
Phase 2
01

Overview

Afimmune is a Dublin-based clinical-stage biotech focused on developing novel therapeutics—primarily small molecule bioactive lipids—for rare and inflammatory diseases. Its lead candidate, Epeleuton, targets sickle cell disease and has shown promising preclinical efficacy with ongoing Phase 2 trials in North America. The company has received orphan drug designation from the FDA for Epeleuton in SCD. Other pipeline assets are at earlier stages of development or have been discontinued for non-core indications such as diabetes mellitus type II.

Therapeutic areas
HematologyImmunologyEndocrinology
Modalities
small molecules (notably synthetic fatty acids such as Epeleuton)bioactive lipids
Industry
Biotech
02

Drug pipeline

3 assets

epeleuton

2

2 more assets in the full pipeline.

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03

Partnerships

Pathway to Cures (venture philanthropy fund of the American National Bleeding Disorders Foundation)member of SCDAA’s SCD C.A.R.E.S. Consortium

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