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AIO-Studien-gGmbH is currently managing multi-center phase 1/2 clinical trials in Germany, notably the GOBLET study, testing combinations of pelareorep (an oncolytic immunotherapeutic virus) with checkpoint inhibitors (atezolizumab) and chemotherapies in gastrointestinal cancers. Initial safety data have been positive, and several cohorts have advanced based on efficacy markers, including robust overall response rates in metastatic pancreatic cancer cohorts[2][4][5].
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