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AIO-Studien-gGmbH has established non-interventional and interventional multi-center clinical research platforms in oncology, notably CRISP for lung cancer and GOBLET (phase 1/2) for advanced/metastatic gastrointestinal tumors; the GOBLET trial showed promising immune activation and disease control rates in first-line metastatic PDAC patients (62% overall response rate, 85% disease control rate, 45% 12-month survival rate)
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