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Akouos developed a pipeline of AAV-mediated gene therapies targeting genetic forms of hearing loss. Its lead candidate AK‑OTOF received FDA clearance for clinical testing and entered a Phase I/II trial designed to treat sensorineural hearing loss caused by OTOF mutations. Other programs target additional genetic causes of deafness and vestibular disorders. The company was acquired by Eli Lilly in late 2022 for up to $610 million
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