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Akyso Pharmaceuticals is developing a proprietary sustained-release, subcutaneous naltrexone implant for opioid use disorder. Preclinical studies have shown safety and efficacy in animal models; IND-enabling toxicology and biocompatibility studies are complete. The first-in-human Phase 1 trial is expected to begin recruitment imminently or has recently started. The product aims to deliver naltrexone over at least six months with tunable release kinetics.
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