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Alfacell Corporation

Somerset/Bloomfield* (*historically Bloomfield; later Somerset per press releases)[3][5][7], New Jersey, United Stateshpalfacell.blogspot.com ↗

Ownership: Private
Development stage: Phase 2

Overview

ONCONASE demonstrated promising results in late-stage clinical trials for malignant mesothelioma and pancreatic cancer. It has received fast track status and orphan-drug designation from the FDA, EU, and Australia. Preclinical studies also showed antiviral activity against SARS-CoV and Dengue virus. The company faced financial challenges but secured private placements to continue development through at least the end of 2010.[2][5][6][7]

Therapeutic areas: OncologyInfectious Diseases
Modalities: Protein therapeutics (ribonucleases/RNases)biologics similar to RNA interference (RNAi)
Industry: Biotech

Drug pipeline

1 asset

ONCONASE

Phase 2

Indications: Non-small cell lung cancer, Malignant mesothelioma

Partnerships

Megapharm Ltd. (Israel)BL&H Co. Ltd. (Korea, Taiwan, Hong Kong)USP Pharma Spolka Z.O.O./US Pharmacia affiliate (Eastern Europe)GENESIS Pharma S.A. (Southeastern Europe)[7]

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