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ALG BioPharm

South San Francisco, California, United Stateslinkedin.com ↗

Ownership: Private
Employees: ~70
Development stage: Other

Overview

Aligos Therapeutics is a clinical-stage biopharmaceutical company with a pipeline focused on liver and viral diseases. Its lead programs include ALG‑055009, a small molecule THR‑β agonist in Phase 2a for MASH that has shown up to 46% reduction in liver fat; ALG‑000184, an oral capsid assembly modulator for CHB with best-in-class sustained reductions in HBV markers through ongoing Phase 1b studies and moving toward Phase 2; ALG‑125755, an siRNA candidate for CHB in early clinical development; and ALG‑097558, a pan-coronavirus protease inhibitor entering externally funded clinical studies for COVID

Therapeutic areas: Metabolic DisordersInfectious Diseases
Modalities: Small moleculeRNA therapy (siRNA)Antiviral agent (protease inhibitor)
Industry: Biotech

Partnerships

Merck [oligonucleotide discovery/development]Emory University [capsid assembly modulator technology]Luxna Biotech [oligonucleotides targeting HBV genome]Katholieke Universiteit Leuven [coronavirus protease inhibitors]Xiamen Amoytop Biotech Co., Ltd. [clinical collaboration]

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