Company intelligence / Profile preview
AliveGen
- Ownership
- Private
- Development stage
- Phase 2
Overview
AliveGen has successfully completed a Phase 1b multiple ascending dose clinical trial for its lead candidate ALG‑801. The study demonstrated safety, tolerability, linear PK exposure, and significant pharmacodynamic responses including muscle gain, fat loss, improved insulin sensitivity, and dual anabolic/anti-resorptive effects on bone. These results support advancement to Phase 2 trials targeting pulmonary arterial hypertension as well as broader metabolic/muscle-wasting conditions. ALG‑801 has received FDA Orphan Drug Designation for PAH.
- Therapeutic areas
- GastroenterologyCardiovascularNephrologyEndocrinologyRare DiseasesNeurology
- Modalities
- Recombinant proteinsFusion proteinsLigand traps (ActRIIA/IIB hybrid ligand trap)
- Industry
- Biotech
Drug pipeline
5 assets4 more assets in the full pipeline.
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