Company intelligence / Profile preview
Allena Pharmaceuticals, Inc.
Newton, Massachusetts, United States
- Ownership
- Private
- Development stage
- Other
01
Overview
Allena Pharmaceuticals developed first-in-class oral enzyme therapeutics targeting difficult-to-treat metabolic diseases. Its lead programs were reloxaliase, a non-systemically absorbed oxalate-degrading enzyme in Phase 3 trials for enteric hyperoxaluria, and ALLN‑346, an orally administered urate-degrading enzyme in Phase 2a trials for patients with gout/hyperuricemia and advanced CKD. Both programs leveraged a proprietary oral biologics platform. The company received Fast Track Designation from the FDA but ceased operations following bankruptcy proceedings completed in mid‑2023.[1][2][3][6]
- Therapeutic areas
- GastroenterologyRare DiseasesNephrology
- Modalities
- Oral enzyme therapeutics (oral biologics)
- Industry
- Biotech
02
Drug pipeline
2 assets1 more asset in the full pipeline.
03
Partnerships
Licensed rights to ALLN–177 from Althea Technologies; no major pharma partnerships disclosed.[9]
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