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Alloksys Life Sciences

Utrecht, Netherlandsalloksys.com ↗
Ownership
Private
Development stage
Phase 3
01

Overview

Alloksys Life Sciences has developed RESCAP®, an alkaline phosphatase-based therapeutic aimed at reducing inflammation-triggered complications in critical care settings. In a Phase IIb trial with patients undergoing cardiothoracic surgery, the primary endpoint of reduced acute kidney injury was not met for the total cohort but was achieved in a subgroup with normal renal function. A continuation into Phase III trials with longer administration times aims to confirm broader benefit. The company also has ongoing or completed studies in burns, rheumatoid arthritis, kidney transplantation, and COVID-related indications[10].

Therapeutic areas
CardiovascularRheumatologyNephrologyImmunologyDermatologyOther
Modalities
Enzyme therapy (alkaline phosphatase-based)Recombinant protein therapeutics
Industry
Biotech
02

Drug pipeline

2 assets

bovine intestinal alkaline phosphatase

3

1 more asset in the full pipeline.

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03

Partnerships

ICM Pharma invested €5.25 million to support phase III trials and registration efforts across Asia-Pacific marketsNational University Heart Centre Singapore leads multicenter trial efforts[7]

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