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Allos Pharma Inc.

Cambridge, Massachusetts, United Statesallospharma.com ↗

Ownership: Private
Development stage: Phase 3

Overview

Allos Pharma is a late-stage pharmaceutical company focused on developing arbaclofen, a small molecule GABA-B receptor agonist, for rare neurological and neurodevelopmental disorders. The company has completed two Phase 3 trials of arbaclofen in Fragile X Syndrome with positive efficacy signals and is preparing for an NDA submission. Arbaclofen also showed promising results in clinical studies for Autism Spectrum Disorder, though primary endpoints were not met; further meta-analysis is planned. The company holds exclusive worldwide rights to develop and commercialize arbaclofen for these indications.[1][2][4]

Therapeutic areas: PsychiatryNeurology
Modalities: Small molecules (notably arbaclofen, a GABA-B receptor agonist)[3][7]
Industry: Biotech

Drug pipeline

1 asset

arbaclofen

Phase 3

Indications: Fragile X Syndrome, Autism Spectrum Disorder

Partnerships

None specifically named; strong collaborations with patient advocacy groups such as the National Fragile X Foundation and FRAXA Research Foundation are noted.[7][8]

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