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Alloy Therapeutics
Waltham, -Massachusetts-, United Statesalloytx.com ↗
- Ownership
- Private
- Employees
- ~100
- Development stage
- Preclinical
01
Overview
Alloy Therapeutics has enabled hundreds of antibody programs to enter the clinic through its partner ecosystem. Its proprietary platforms have demonstrated increased potency or expanded target reach compared to traditional approaches. For example, the AntiClastic antisense format has shown significant potency improvements over gapmer ASOs in preclinical studies. Clinical results are reported by partner companies rather than by Alloy directly.
- Therapeutic areas
- OphthalmologyRare Diseases
- Modalities
- Monoclonal antibodies (mAbs)Bispecific antibodiesTCR mimics (TCRms)Engineered T-cell receptors (TCRs)Antisense oligonucleotides (ASOs)PeptidesCell therapiesDrug delivery technologies
- Industry
- Drug Discovery Services
02
Partnerships
Pfizer – collaboration on new antibody discovery platformsSanofi – collaboration using AntiClastic antisense platform technologyMaze Therapeutics – co-founded Broadwing Bio JV targeting ophthalmic diseases with biologic drugs based on Maze’s genomics insightsPyxis Oncology – co-founded Voxall Therapeutics JV for novel oncology/immunology treatmentsTegmine Therapeutics – advancing solid tumor treatments via antibody-based therapeutics
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