Allume Systems

Alume Biosciences is a clinical-stage biotechnology company specializing in the development of nerve-highlighting agents for fluorescence-guided surgery. The company's lead candidate, ALM-488, is a fluorescently labeled peptide-dye conjugate that binds to the extracellular matrix of nerves, allowing surgeons to visualize them in real-time using fluorescence-enabled imaging systems. This technology is designed to reduce the risk of accidental nerve injury during complex surgical procedures, such as head and neck or spine surgeries. Founded by Dr. Quyen Nguyen and the late Nobel Laureate Roger Tsien, Alume is currently advancing its lead program through pivotal Phase 3 clinical trials to improve surgical precision and patient outcomes.