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Alpenglow Biosciences
Seattle, Washington, United Statesalpenglowbiosciences.com ↗
- Ownership
- Private
- Development stage
- Commercial
01
Overview
Alpenglow Biosciences has developed a patented AI-powered open-top light-sheet microscopy platform that enables non-destructive digitization of entire tissues in three dimensions. Their Aurora™ system integrates advanced imaging hardware with automated data management and deep-learning-based image analysis to provide unprecedented insight into tissue architecture. The company’s assays—such as the “3D Derm Score” for dermatology and “3D I/O Pro Assay” for immuno-oncology—are currently available for research use only. Five of the top ten pharmaceutical companies are customers or partners. The company has secured over $24M from ARPA-H/NIH grants to accelerate its transition from biopharma research tool to high-impact clinical assay provider.
- Therapeutic areas
- OncologyImmunologyOtherDermatologyNeurology
- Modalities
- Device (AI-enabled 3D imaging platform)Non-pharmacological therapy (enabling technology for drug development and diagnostics)Software (AI-driven analysis and spatial profiling tools)
- Industry
- Pathology
02
Partnerships
ZEISS Research Microscopy Solutions – co-development of inverted light-sheet microscope/bioinformatics pipeline tailored to clinical pathology applicationsMolecular Instruments – partnership on high-resolution RNA imaging using HCR Gold reagents with Alpenglow’s HOTLS systemPharmaceutical partners include five of the top ten pharma companies globally; named customers include GlaxoSmithKline (“GSK”), Mayo Clinic, Incyte Therapeutics.
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