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Alpheus Medical’s sonodynamic therapy platform has shown promising early results. In a Phase 1/2 trial for recurrent or refractory high-grade gliomas, median overall survival was doubled and progression-free survival improved threefold compared to historical data. The treatment demonstrated a strong safety profile, selectively targeting cancer cells while sparing healthy tissue. A randomized controlled Phase 2B trial in newly diagnosed GBM is planned for further validation.
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