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Alpheus Medical

Oakdale, Minnesota, United Statesalpheusmedical.com ↗

Ownership: Private
Development stage: Phase 1

Overview

The company’s first-in-human Phase 1/2 trial for recurrent or refractory high-grade gliomas demonstrated a strong safety profile. Median overall survival was doubled and progression-free survival improved threefold compared to historical data. The therapy selectively targets cancer cells while sparing healthy tissue. FDA Orphan Drug and Fast Track designations have been granted for their lead program.[3][4][6][7][9]

Therapeutic areas: Oncology
Modalities: Sonodynamic therapy (SDT)drug-device combination (Low-intensity Diffuse Ultrasound + oral 5-Aminolevulinic Acid)
Industry: Biotech

Drug pipeline

1 asset

5-aminolevulinic acid

Phase 1

Indications: Glioblastoma, High-grade glioma

Partnerships

OrbiMed Advisors (investor/supporter)[2][8]Action Potential Venture Capital (investor/supporter)[2]Medtech Convergence Fund/SV Health Investors[8]Brain Tumor Investment Fund/National Brain Tumor Society affiliate[8]BrightEdge/American Cancer Society impact investment arm[4][7]

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