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ALS Therapy Development Institute

Cambridge, Massachusetts, United Statesals.net ↗
Ownership
Private
Employees
~200
Development stage
Phase 2
01

Overview

ALS Therapy Development Institute has developed several preclinical candidates for ALS. Its most advanced asset, AT‑1501, a monoclonal antibody targeting CD40L/CD154, has entered clinical testing as a potential treatment for ALS. The institute also runs large-scale patient data initiatives like the Precision Medicine Program/ALS Research Collaborative to accelerate discovery and development of new therapeutics[5][8].

Therapeutic areas
Neurology
Modalities
Small moleculesProtein biologicsGene therapiesCell-based constructs
Industry
Academic Hospital/University/Research
02

Drug pipeline

1 asset

tegoprubart

Phase 2
Indications
Amyotrophic Lateral Sclerosis (ALS)
03

Partnerships

Muscular Dystrophy Association (“Augie’s Quest” initiative)Regenesance (Netherlands)Neurotune (Switzerland)Gladstone Institutes (USA)various academic collaborations

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