ARX517
Phase 1/2- Indications
- Metastatic castration-resistant prostate cancer
Company intelligence / Profile preview
Ambrx
La Jolla, California, United Statesambrx.com ↗
- Ownership
- Public · AMAM
- Employees
- ~200
- Development stage
- Phase 1
01
Overview
Ambrx has demonstrated promising early clinical results with its lead ADCs. ARX517 showed preliminary safety and efficacy in advanced prostate cancer patients at ESMO2023. ARX788 has advanced through Phase I trials for HER2-positive cancers. The company’s technology enables highly stable, site-specific ADCs designed to improve therapeutic index over conventional approaches.[1]
- Therapeutic areas
- Oncology
- Modalities
- Antibody-drug conjugates (ADCs)Bispecific antibodiesModified cytokinesProtein therapeutics[1][3][6]
- Industry
- Biotech
02
Drug pipeline
3 assets2 more assets in the full pipeline.
03
Partnerships
Multiple collaborations with major pharmaceutical companies on drug candidates generated using Ambrx technology; specific partners not named in the provided sources but historically included large pharma and Chinese investors.[4]
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