AMC Cardiovascular Sciences

AMC Cardiovascular Sciences was a biotechnology company focused on the development of novel therapeutics for the treatment of cardiovascular diseases, specifically targeting ischemia-reperfusion injury. The company's lead research centered on small molecule inhibitors of the sodium-calcium exchanger (NCX), a critical protein involved in calcium homeostasis during cardiac stress. By modulating NCX activity, the company aimed to prevent the cellular damage that occurs when blood flow is restored to the heart after a myocardial infarction or during cardiac surgery. Despite promising early-stage research, the company is no longer active in the clinical development space.