Company intelligence / Profile preview
Amplo Biotechnology
Towson, Maryland, USAamplobiotechnology.com ↗
- Ownership
- Private
- Employees
- ~3
- Development stage
- Preclinical
01
Overview
Amplo’s lead program AMP-101 has demonstrated promising preclinical pharmacology and safety data in mouse models of Dok7 CMS. The therapy showed functional correction of the disease phenotype and extended lifespan in animal studies. Manufacturing at scale with high purity has been achieved. AMP-201 also shows efficacy in preclinical models for ColQ CMS. Both programs are expected to enter clinical trials soon.
- Therapeutic areas
- Rare DiseasesNeurology
- Modalities
- Gene therapyAdeno-associated virus (AAV)-based gene therapy
- Industry
- Biotech
02
Drug pipeline
3 assets2 more assets in the full pipeline.
03
Partnerships
Nagoya University/Professor Kinji Ohno’s laboratory – exclusive license for AAV-ColQ data supporting AMP‑201 developmentUniversity of California Davis/Professor Ricardo Maselli – collaboration on AMP‑201 development and clinical translationUniversity of Tokyo – exclusive license agreement for DOK7/AAV technology supporting AMP‑101 development
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