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Before its acquisition, ANA Therapeutics was developing ANA-001, an oral capsule formulation of niclosamide repurposed as an antiviral/anti‑inflammatory for hospitalized patients with moderate to severe COVID‑19 (not requiring ventilators), in a two‑part Phase 2/3 trial initiated in October 2020 under the 505(b)(2) pathway.[1] The first 60‑patient Phase 2 portion focused on safety and tolerability with secondary efficacy and PK endpoints; topline data were expected in 2021, but no public late‑stage efficacy results are available in the acquisition materials.[1]
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