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AnaptysBio’s lead asset, rosnilimab, a PD‑1 depleter and agonist, has demonstrated “best-in-disease” efficacy in a robust global Phase 2b trial for moderate-to-severe rheumatoid arthritis with durable responses off drug and favorable safety compared to standard of care biologics or JAK inhibitors. Other clinical-stage programs include ANB032 (BTLA agonist) for atopic dermatitis. The company also has preclinical assets targeting CD122 and BDCA2. Multiple antibodies discovered by AnaptysBio have been licensed to partners such as GSK for immuno-oncology applications[6][5][3].
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