Company intelligence / Profile preview

Ankyra Therapeutics

Cambridge, Massachusetts, United Statesankyratx.com ↗
Ownership
Private
Development stage
Preclinical
01

Overview

Preliminary data from the ongoing Phase 1 ANCHOR study of tolododekin alfa (ANK‑101) show that the anchored IL‑12 drug can be delivered at higher local doses than previously possible without systemic toxicity. The trial demonstrated increased CD8+ T cell infiltration and PD-L1 expression in treated tumors. Combination cohorts with checkpoint inhibitors have begun dosing patients

Therapeutic areas
Oncology
Modalities
Anchored cytokine immunotherapies (notably anchored interleukin-12)Drug conjugates
Industry
Biotech
02

Drug pipeline

12 assets

tolododekin alfa

1

11 more assets in the full pipeline.

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03

Partnerships

Merck & Co.: Clinical trial collaboration to evaluate ANK–101 with KEYTRUDA® (pembrolizumab)Johnson & Johnson Lung Cancer Initiative for early clinical evaluation of ANK–101 in lung cancerJenga Biosciences licensed veterinary rights to canine version of platform/JEN–101 for animal health applications

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