Company intelligence / Profile preview

Appello Pharmaceuticals

Nashville, Tennessee, USAappellopharma.com ↗
Ownership
Private
Employees
~49
Development stage
Phase 1
01

Overview

Appello Pharmaceuticals is advancing its lead compound AP-472 through clinical trials for Parkinson's disease treatment. The company completed a Phase 1a study where AP-472 was detected in the cerebrospinal fluid of healthy volunteers at levels predicted to be required for efficacy, indicating the drug is brain penetrant. A Phase 1b trial was planned to enroll approximately 20 Parkinson's disease patients with results expected in early 2023.

Therapeutic areas
PsychiatryNeurology
Modalities
Small molecules
Industry
Biotech
02

Drug pipeline

1 asset

AP-472

2
03

Partnerships

Vanderbilt University's Warren Center for Neuroscience Drug Discovery (WCNDD)

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