Apple Tree Partners does not have clinical results of its own but has backed numerous successful biotech and medtech companies through all development stages. Portfolio highlights include Marengo Therapeutics’ T cell agonist programs in solid tumors and Aulos Bioscience’s IL‑2 therapeutics for cancer.
Portfolio company examples:
Marengo Therapeutics – advancing dual T cell agonists for PD‑1 resistant solid tumors
Gala Therapeutics – medical devices for chronic bronchitis
Nine Square Therapeutics – small molecules for movement disorders
Aulos Bioscience – computationally designed antibodies targeting IL‑2 pathway in cancer
Pipeline breadth and details are specific to each portfolio company.
Therapeutic areas
OncologyPulmonologyNeurology
Modalities
Small moleculeMonoclonal antibodyMedical device
Industry
Investors
02
Drug pipeline
2 assets
AU-007
Phase 2
Indications
Melanoma
1 more asset in the full pipeline.
03
Partnerships
Portfolio companies have partnerships with major pharma such as Novo Nordisk (Deep Apple Therapeutics), but ATP itself acts as the investor/founder rather than partner.
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