Applied Genetics Inc. Dermatics

AGI Dermatics is a biotechnology company specializing in the development of DNA repair enzymes for skincare and dermatological applications. Founded by Dr. Daniel Yarosh, the company pioneered the use of liposome-encapsulated enzymes to repair UV-induced DNA damage in the skin. Their proprietary technologies, including Ultrasomes, Photosomes, and Roxisomes, deliver specific enzymes like T4 endonuclease V and 8-oxoguanine glycosylase directly to skin cells. These innovations are designed to prevent skin cancer and reverse the signs of photoaging by correcting DNA lesions before they lead to permanent mutations. The company's lead therapeutic candidate, T4N5 liposome lotion, reached Phase 3 clinical trials for patients with xeroderma pigmentosum. In 2008, AGI Dermatics was acquired by The Estée Lauder Companies to integrate its advanced DNA repair science into their global skincare portfolio.