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Apreo Health has completed first-in-human, multicenter feasibility studies ("BREATHE 1&2") for its BREATHE Airway Scaffold, enrolling 60 patients across five sites in Australia and Europe. Six-month data demonstrated early feasibility, safety, and efficacy—showing improvements in lung function, symptoms, and quality of life without the risk of pneumothorax. The therapy is designed to be tissue-sparing and broadly applicable to severe emphysema patients with hyperinflation who are underserved by current interventions[1][3].
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