Company intelligence / Profile preview

Aptevo Therapeutics

Seattle, Washington, United Statesaptevotherapeutics.com ↗
Ownership
Public · APVO
Employees
~37
Development stage
Phase 1
01

Overview

Aptevo’s lead candidate Mipletamig has shown promising results in AML with high remission rates reported in the RAINIER trial. ALG.APV‑527 has demonstrated stable disease in a significant proportion of patients with solid tumors during dose escalation studies. Three additional candidates are at the preclinical stage targeting various tumor types.

Therapeutic areas
Oncology
Modalities
Bispecific antibodies (bispecific immunotherapies)Multi-specific immunotherapeutic proteins
Industry
Biotech
02

Drug pipeline

10 assets

mipletamig

1

9 more assets in the full pipeline.

03

Partnerships

Alligator Bioscience AB – co-development of ALG.APV–527 for solid tumorsCMC ICOS Biologics – manufacturing partnership for supply of clinical materialsEmergent BioSolutions Inc. – historical agreements including trademark licensing and manufacturing services after spin-out from Emergent BioSolutions Inc.Midcap Financial Trust – financial agreement partnerPiper Jaffray & Co., Lincoln Park Capital Fund – financial partners/investorsSaol International Limited/Venus Bio Therapeutics Sub LLC – transaction partners on asset sales/acquisitions
04

Financials

Market cap
$2.8M
Total revenue
$0
Enterprise value
$-2.8M

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