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Apthera developed NeuVax, a peptide-based immunotherapy designed for adjuvant treatment of low-to-intermediate HER2+ breast cancer not eligible for Herceptin. NeuVax showed positive results in Phase 2 for disease free survival and was cleared to enter a pivotal Phase 3 trial under FDA Special Protocol Assessment before Apthera was acquired by RXi Pharmaceuticals in 2011[1][4].
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