Company intelligence / Profile preview
Aquinnah Pharmaceuticals
Cambridge, Massachusetts, United Statesaquinnahpharma.com ↗
- Ownership
- Private
- Employees
- ~2
- Development stage
- Preclinical
01
Overview
Aquinnah has demonstrated preclinical efficacy for its lead oral small molecule targeting tau-stress granule interactions in advanced animal models of Alzheimer’s disease, showing ~70% reduction in pathological tau. The compound is designed as a once-daily pill with potential to combine with anti-amyloid drugs. ALS programs target TDP-43 pathology using similar approaches. No clinical trial results yet; most programs are preclinical or IND-enabling.
- Therapeutic areas
- Neurology
- Modalities
- small molecules
- Industry
- Biotech
02
Drug pipeline
2 assets1 more asset in the full pipeline.
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Partnerships
Roche – collaboration to advance brain penetrant oral small molecules for ALS and neurodegenerative diseases; previously partnered with Pfizer on investment/funding
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