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Ardsley Pharmaceuticals
Waltham, Massachusetts, United Statesardelyx.com ↗
- Ownership
- Private
- Development stage
- Other
01
Overview
Ardelyx has successfully commercialized two first-in-class medicines based on its proprietary research into gut transporters. IBSRELA® (tenapanor) treats irritable bowel syndrome with constipation and XPHOZAH® (tenapanor) addresses hyperphosphatemia in chronic kidney disease patients on dialysis. Both drugs are approved by the FDA. The company continues to advance additional candidates targeting renal and gastrointestinal diseases through its unique mechanism-of-action approach.
- Therapeutic areas
- GastroenterologyNephrology
- Modalities
- Small molecules (notably NHE3 inhibitors such as tenapanor)
- Industry
- Biotech
02
Partnerships
AstraZeneca—previous licensing/development partnership for tenapanor/RDX5791 program; AstraZeneca paid upfront/milestone payments but current status appears that rights reverted or were not fully outlicensed long-term.
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