Company intelligence / Profile preview

Argonaute RNA

Bristol/Cardiff, England/Wales, United Kingdomargonauterna.com ↗
Ownership
Private
Employees
~7
Development stage
Preclinical
01

Overview

Argonaute RNA develops proprietary dual-siRNA therapeutics using its PULSE siRNA™ platform, enabling simultaneous silencing of two genes. The approach aims to address complex, multifactorial diseases where targeting a single gene may be insufficient. Their technology focuses on safe, effective, and temporary gene silencing with improved stability over traditional siRNAs. The company has deep industry expertise in taking programs from early-stage through Phase II trials but current pipeline details suggest preclinical/IND-enabling status for most assets.

Therapeutic areas
OncologyCardiovascularRare Diseases
Modalities
small interfering RNAs (siRNA)dual siRNA constructs
Industry
Biotech
02

Drug pipeline

1 asset

ANGPTL3/DGAT2 bispecific siRNA

Preclinical
03

Partnerships

CatSci – collaboration for manufacturing high-quality siRNA drug substance for robust preclinical studies and scale-up for clinical trials.Carbometrics – partnership to enhance bioconjugation/synthetic chemistry aspects of the platform.

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