ARO Cinch
Pre-clinical- Indications
- Spinal disc herniation
Company intelligence / Profile preview
The company’s lead candidate, ABX1100, has demonstrated favorable safety and tolerability in phase 1 studies with healthy volunteers, showing approximately a 70% reduction in GYS1 mRNA and protein at ten weeks post-dosing. The drug has advanced to an open-label Phase 1 trial in patients with late-onset Pompe disease. Initial clinical data are expected to be presented in mid-to-late 2024. Preclinical programs are ongoing for autoimmune disorders.
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