Company intelligence / Profile preview

Arrowhead Pharmaceuticals

Pasadena, California, United Statesarrowheadpharma.com ↗
Ownership
Public · ARWR
Employees
~376
Development stage
Phase 3
01

Overview

Arrowhead’s lead asset plozasiran achieved successful topline results in the pivotal Phase 3 PALISADE study for familial chylomicronemia syndrome. The New Drug Application was accepted by the FDA with a PDUFA date set for November 2025. Additional late-stage programs target severe hypertriglyceridemia and mixed hyperlipidemia. The company has a broad pipeline leveraging its proprietary TRiM™ RNAi platform across cardiometabolic, liver-related rare diseases, pulmonary conditions, hepatitis B infection and genetic muscle disorders. Several assets are partnered with major pharmaceutical companies.

Therapeutic areas
Metabolic DisordersPulmonologyGastroenterologyCardiovascularNeurologyInfectious Diseases
Modalities
RNA interference (RNAi) therapeutics
Industry
Biotech
02

Drug pipeline

36 assets

plozasiran

Approved

35 more assets in the full pipeline.

03

Partnerships

Amgen – cardiovascular collaboration/licensing agreement for ARO-LPA & ARO-AMG1Janssen – $3.7B license/collaboration agreement for ARO-HBV & up to three additional targetsTakeda – partnership on fazirsiranSarepta Therapeutics – recent licensing/collaboration agreement covering neuromuscular assets outside core focus area
04

Financials

Market cap
$8.1B
Total revenue
$829.4M
Enterprise value
$7.4B

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