Company intelligence / Profile preview
Arrowhead Pharmaceuticals
Pasadena, California, United Statesarrowheadpharma.com ↗
- Ownership
- Public · ARWR
- Employees
- ~376
- Development stage
- Phase 3
01
Overview
Arrowhead’s lead asset plozasiran achieved successful topline results in the pivotal Phase 3 PALISADE study for familial chylomicronemia syndrome. The New Drug Application was accepted by the FDA with a PDUFA date set for November 2025. Additional late-stage programs target severe hypertriglyceridemia and mixed hyperlipidemia. The company has a broad pipeline leveraging its proprietary TRiM™ RNAi platform across cardiometabolic, liver-related rare diseases, pulmonary conditions, hepatitis B infection and genetic muscle disorders. Several assets are partnered with major pharmaceutical companies.
- Therapeutic areas
- Metabolic DisordersPulmonologyGastroenterologyCardiovascularNeurologyInfectious Diseases
- Modalities
- RNA interference (RNAi) therapeutics
- Industry
- Biotech
02
Drug pipeline
35 assets34 more assets in the full pipeline.
Request access →03
Partnerships
Amgen – cardiovascular collaboration/licensing agreement for ARO-LPA & ARO-AMG1Janssen – $3.7B license/collaboration agreement for ARO-HBV & up to three additional targetsTakeda – partnership on fazirsiranSarepta Therapeutics – recent licensing/collaboration agreement covering neuromuscular assets outside core focus area
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