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Asha Therapeutics is advancing a pipeline of novel, disease-modifying therapeutics for neurodegenerative and neuromuscular diseases. Their lead candidates—ASHA-624 (a SARM1 inhibitor) and ASHA-091 (a DRP1 inhibitor)—has demonstrated robust efficacy and safety in preclinical models. Both are expected to enter first-in-human clinical trials by late 2024[3][5][6]. The company’s PRISM™ platform enables rapid de novo drug design targeting previously undruggable proteins.
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