Company intelligence / Profile preview

AskGene Pharma

Camarillo, California, United Statesask-gene.com ↗
Ownership
Private
Development stage
Phase 3
01

Overview

AskGene’s lead asset ASKB589, a second-generation anti-Claudin18.2 monoclonal antibody with ADCC enhancement, has entered pivotal Phase III trials in China for first-line treatment of advanced gastric and gastroesophageal junction cancers in combination with chemotherapy and a PD‑1 inhibitor. Over two hundred patients have been enrolled across earlier studies with no dose-limiting toxicities observed to date; maximum tolerated dose not yet reached as of early clinical data reporting. The company also has multiple cytokine prodrug programs leveraging its proprietary SmartKine® platform at various stages from preclinical to clinical development.[6][8][9]

Therapeutic areas
OphthalmologyOncologyImmunologyInfectious Diseases
Modalities
Monoclonal antibodies (mAbs)Fusion proteinsAntibody fusion proteinsBispecific antibodiesRecombinant polypeptides[5][8]
Industry
Biotech
02

Drug pipeline

11 assets

ASKB589

3

10 more assets in the full pipeline.

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